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The beta-HIVS-induced reduce of dUTPase from the phosphoprotein fraction of DMS114 cells was verified applying immunoblotting. Therapy from the cells with beta-HIVS-induced immediate reduction of dUTPase exercise. An antioxidant N-acetyl-cysteine inhibited equally the reduction of phosphorylated dUTPase plus the induction of apoptosis by beta-HIVS